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The skin of non-organic fruits and vegetables contain pesticides and may cause allergic reactions and if you are thinking of using a sausage... nitrites and other nasty preservatives would be a big reason to avoid them. Also, people who have allergies to ragweed will definitely want to stay away from cucumbers, melons, bananas, and a few others.
Using a condom over items is a good way to protect yourself, but make sure to wash your hands and consider that the condom may roll off. If you use plastic wrap, just make sure you are not allergic to it.
Anyone who has had a UTI (Urinary Tract Infection) will tell you it is rather painful, so making sure not to introduce anything that could irritate the urethra (pee hole) like bacteria is very important. Also, staying away from sugar in the vaginal opening is a good idea... (candy, popsicles, etc.) can lead to a nasty yeast infection.
Make Sure You Can Easily Remove It
Working in hospitals, I have heard many insane Emergency Room stories of patients putting things inside them that made any sane person scratch their head in disbelief. Like the woman who got splinters from her broom handle, the man who couldn't relocate his vibrating pager in a plastic baggy...
Common sense says not to get a lit candle too close to your pubic hair or not to use electrical items that are not meant for contact with moist or wet areas for sex play but I can assure you people have tried. Please, just think it through and use common sense should you have a creative moment about what "cool idea" you could try.
Your Genital & Anal Skin Are Delicate
Make sure to keep in mind that anything like a vibrating toothbrush or base of an electric razor may feel good at first, however material that is course may rub your delicate skin raw if applied for too long or hard. Also, make sure that what you are using does not have a crevice that can grab some of your skin and pinch because your intended erotic experience may have the kind of screaming that comes from pain not pleasure.
That is part of why we review our sex toys... because even some sex toy manufacturers out to make a quick buck can use toxic materials or make a harmful product. If you want the best, make sure to see the following articles on the safest, healthy and best that is out there, because you deserve it!