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New
HIV Therapy
Researchers
may finally be on track to fight the AIDS virus by blocking
a long-elusive target, an HIV enzyme called integrase. An experimental
drug that inhibits the enzyme helped to keep the infection in
check in monkeys.
Today, there
are two approaches to fighting HIV. One new drug, called Fuzeon,
works by preventing HIV from invading immune-system cells. Numerous
older drugs work after the virus has invaded those cells, by
blocking two of the three enzymes - reverse transcriptase and
protease - that HIV uses to incorporate its genes into cells
and to spread.
Combinations
of those drugs have helped thousands of patients live longer
and healthier. But these drugs are not a cure and they gradually
lose their effectiveness. So new approaches are needed, especially
as the epidemic continues to rise.
The United
Nations counts a record 5 million people worldwide infected
by HIV last year, with 3 million killed. That explains the interest
in the third enzyme, integrase, which is crucial to the actual
melding of HIV genes with patients' own DNA.
Far more
research is needed to prove if Merck & Co.'s approach really
can block this enzyme's crucial work in helping HIV reproduce
and spread.
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"It
is bad enough that people are dying of AIDS, but no one should
die of ignorance."-Elizabeth Taylor.
HIV
& Aids Internet Resources-
AIDS/HIV
Hotline:1-800-342-AIDS
- Adolescent
AIDS Program: Children's Hospital at Montifiore
http://www.adolescentaids.org/
Based in the Bronx, New York, the Adolescent AIDS Program
at the Children's Hospital at Montefiore Medical Center
serves as a local and national resource for those living
with HIV/AIDS; adolescents who are at-risk for HIV infection;
healthcare providers who treat adolescents living with
or at-risk for HIV infection; and lesbian, gay, bisexual,
transgender or questioning adolescents, their families
and caregivers.
- AIDS
Education Global Information System http://www.aegis.com
HIV/AIDS Daily Briefing
- Critical
Path AIDS Project http://tensegrity.critpath.org/cpap/
Seeks to provide a key set of materials and links on HIV/AIDS
treatment, research issues and activists skills, as well
as connections to allied movements.
- American
Social Health Association (ASHA) http://www.ashastd.org/
ASHA is dedicated to improving the health of individuals,
families, and communities, with a focus on preventing
sexually transmitted diseases and their harmful consequences.
- American
Foundation for AIDS Research Far (AmfAR) http://www.amfar.org
Dedicated to the support of AIDS research, AIDS prevention,
treatment education, and the advocacy of sound AIDS-related
public policy.
- AVERT
Home Page http://www.avert.org/
The site emphasises HIV/AIDS prevention, and there is
a large and very popular section for young people. But
there is also help provided for HIV positive people, with
new pages on HIV treatment, extra pages of stories from
people living with HIV and AIDS, and a new section on
HIV/AIDS in Africa.
- The
Body: A Multimedia AIDS and HIV Information Resource
http://www.thebody.com/index.html
Mission: 1) Use web to lower barriers between patients
and clinicians; 2) demystify HIV/AIDS and its treatment;
3) Improve patients quality of life and 4) foster community
through human connection.
- Center
for AIDS Prevention Studies (CAPS) http://www.epibiostat.ucsf.edu/capsweb/
CAPS, at the University of San Francisco, conducts rigorous
theory-based research that will have maximum impact on
the theory, practice, and policy of AIDS prevention.
- Center
for Disease Control's National Prevention Information
Network (CDCNPIN) http://www.cdcnpin.org/
CDCNPIN is the U.S. reference, referral, and distribution
service for information on HIV/AIDS, sexually transmitted
diseases (STDs), and tuberculosis (TB). NPIN produces,
collects, catalogs, processes, stocks, and disseminates
materials and information on HIV/AIDS, STDs, and TB to
organizations and people working in those disease fields.
- Henry
J. Kaiser Family Foundation's Daily Health Reports on
HIV/AIDS http://www.kaisernetwork.org/daily_reports/rep_hiv.cfm
- HIV
InSite http://hivinsite.ucsf.edu
Comprehensive, up-to-date information on HIV/AIDS treatment,
education and policy from the University of California,
San Francisco
-
HIV
Vaccine Trials Network http://www.hvtn.org
The HIV Vaccine Trials Network is an international partnership
of research scientists, clinical trial sites, and community
representatives working in the global search for a preventive
HIV vaccine. Learn more about how you can get in involved
with a trial site in your area.
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-
The
AIDS Memorial Quilt
http://www.aidsquilt.org
The AIDS Memorial Quilt is a poignant memorial, a powerful
tool for prevention education and the largest ongoing
community arts project in the world.
-
National
Institute of Allergy and Infectious Diseases (NIAID) Division
of Acquired Immunodeficiency Syndrome http://www.niaid.nih.gov/daids/
Formed to increase basic knowledge of the pathogenesis,
natural history, and transmission of HIV disease and to
support research that promotes progress in its detection,
treatment, and prevention.
-
UNAIDS
- Joint United Nations Programme on HIV/AIDS http://www.unaids.org
As the main advocate for global action on HIV/AIDS,
UNAIDS leads, strengthens and supports an expanded response
aimed at preventing the transmission of HIV, providing
care and support, reducing the vulnerability of individuals
and communities to HIV/AIDS, and alleviating the impact
of the epidemic.
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Our
Rating
Out Of Four Stars-
Category-
Drama
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And The
Band Played On
One
of our readers wanted us to mention this movie as
they felt it was a great one and we agree.
This
superior, made-for-cable film in 1993, this Home Box
Office adaptation of Randy Shilts' chronicle detailing
the emergence of AIDS in America and the fight against
bureaucracy and society for a cure is a taut, outrageous,
and affecting true-life drama.
Matthew
Modine (Birdy, Married to the Mob) is featured as
a doctor with the Centers for Disease Control at the
time when the first reports of a disease plaguing
the gay community were heard. Modine and his colleagues
embark on an investigation that resembles a compelling
detective story as they try to track the source of
the disease and discover a cure. Their efforts are
thwarted by an ambivalent government and a turf war
between French physicians and a celebrated American
researcher (Alan Alda) who seems to place his own
glory above the dead and the dying. Featuring heartfelt
performances from a stellar cast including Richard
Gere, Glenne Headly, Anjelica Huston, Steve Martin,
Ian McKellen, Saul Rubinek, and Lily Tomlin, this
impassioned film stands as an impressive and important
document of one of the darkest eras in modern human
history, and a tribute to the spirit of those who
sought to save lives.
--Robert Lane
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